Mediterranean diet slashes risk of heart disease, early death in women

Women who follow the Mediterranean diet have nearly 25% less chance of heart disease and early death, according to a new analysis.

Research from a team at the University of Sydney published in the journal Heart looked at data from 16 studies done between 2003 and 2021.

The participants in the studies were mainly from the US and Europe and consisted of more than 700,000 women aged 18 years and older, and their cardiovascular health was monitored for 12.5 years on average.

Findings suggest that closely following a Mediterranean diet lowered the risk of cardiovascular disease by 24% — 25% lower for coronary heart disease specifically — and the risk of death from any cause by 23%

The Mediterranean diet — which was named the 2023 best diet overall for the sixth year in a row by U.S. News & World Report — stresses the importance of quality sourcing and filling your plate with nutrient-rich whole foods and grains, with an emphasis on fresh produce, lean protein, such as fish and chicken, and, of course, antioxidant-rich olive oil.

The Med diet derives from the traditional diets of 21 countries that border the Mediterranean Sea, including Italy, Greece, Croatia, Turkey and Monaco — where fresh greens, fruits, fish, nuts and olives abound.


Close-up view of a bowl of fresh green salad with mozzarella, mixed nuts and dry fruits. A womanâs hand was pouring olive oil into the salad.
The Mediterranean diet was named the 2023 best diet overall for the sixth year in a row.
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It’s unclear why this diet specifically is beneficial for women, and further sex-specific research would have to be done to guide clinical practices.

“Mechanisms explaining the sex-specific effect of the Mediterranean diet on cardiovascular disease and death remain unclear,” study author Dr. Sarah Zaman said. “Female-specific cardiovascular risk factors, including premature menopause, pre-eclampsia and gestational diabetes, or female predominant risk factors, such as systemic lupus, can all independently increase cardiovascular disease risk.”

Heart disease is the leading cause of death for women in the US, according to the CDC. In 2020, it was the cause of about one in every five female deaths.


Grilled Halibut with Spinach, leeks and Pine Nuts - Photographed on Hasselblad H3D2-39mb Camera
Findings suggest that closely following a Mediterranean diet lowered the risk of cardiovascular disease by 24%.
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Zaman continued, “It is possible that preventative measures, such as a Mediterranean diet, that targets inflammation and cardiovascular disease risk factors, impose differing effects in women compared with men.”

An earlier study from Harvard University said the Mediterranean diet was one of four common healthy eating patterns that can help reduce the risk of early death by up to 20%.